Single Chain Antibodies as Tools to Study transforming growth factor-β-Regulated SMAD Proteins in Proximity Ligation-Based Pharmacological Screens

The cellular heterogeneity seen in tumors, with subpopulations of cells capable of resisting different treatments, renders single-treatment regimens generally ineffective. Accordingly, there is a great need to increase the repertoire of drug treatments from which combinations may be selected to effi...

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Publicat a:Mol Cell Proteomics
Autors principals: Blokzijl, Andries, Zieba, Agata, Hust, Michael, Schirrmann, Thomas, Helmsing, Saskia, Grannas, Karin, Hertz, Ellen, Moren, Anita, Chen, Lei, Söderberg, Ola, Moustakas, Aristidis, Dübel, Stefan, Landegren, Ulf
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Biochemistry and Molecular Biology 2016
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5083110/
https://ncbi.nlm.nih.gov/pubmed/26929218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M115.055756
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