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Melanoma cells constitutively release an anchor-positive soluble form of protectin (sCD59) that retains functional activities in homologous complement-mediated cytotoxicity.

Protectin (CD59), a glycosylphosphatidylinositol-anchored cell membrane glycoprotein, is differentially expressed on melanocytic cells and represents the main restriction factor of C-mediated lysis of melanoma cells. In this study, we report that CD59-positive melanoma cells constitutively release a...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Principais autores: Brasoveanu, L I, Fonsatti, E, Visintin, A, Pavlovic, M, Cattarossi, I, Colizzi, F, Gasparollo, A, Coral, S, Horejsi, V, Altomonte, M, Maio, M
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508302/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9276743/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119638
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