Identification of an obesity quantitative trait locus on mouse chromosome 2 and evidence of linkage to body fat and insulin on the human homologous region 20q.

Chromosomal synteny between the mouse model and humans was used to map a gene for the complex trait of obesity. Analysis of NZB/BINJ x SM/J intercross mice located a quantitative trait locus (QTL) for obesity on distal mouse chromosome 2, in a region syntenic with a large region of human chromosome...

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Main Authors: Lembertas, A V, Pérusse, L, Chagnon, Y C, Fisler, J S, Warden, C H, Purcell-Huynh, D A, Dionne, F T, Gagnon, J, Nadeau, A, Lusis, A J, Bouchard, C
Format: Artigo
Sprog:Inglês
Udgivet: 1997
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC508301/
https://ncbi.nlm.nih.gov/pubmed/9276742
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