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Mechanisms of CO(2)/H(+) Sensitivity of Astrocytes

Ventral regions of the medulla oblongata of the brainstem are populated by astrocytes sensitive to physiological changes in P(CO2)/[H(+)]. These astrocytes respond to decreases in pH with elevations in intracellular Ca(2+) and facilitated exocytosis of ATP-containing vesicles. Released ATP propagate...

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Veröffentlicht in:J Neurosci
Hauptverfasser: Turovsky, Egor, Theparambil, Shefeeq M., Kasymov, Vitaliy, Deitmer, Joachim W., del Arroyo, Ana Gutierrez, Ackland, Gareth L., Corneveaux, Jason J., Allen, April N., Huentelman, Matthew J., Kasparov, Sergey, Marina, Nephtali, Gourine, Alexander V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5083006/
https://ncbi.nlm.nih.gov/pubmed/27798130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1281-16.2016
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