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Mechanical Flexibility Reduces the Foreign Body Response to Long-Term Implanted Microelectrodes in Rabbit Cortex

Micromotion between the brain and implanted electrodes is a major contributor to the failure of invasive microelectrodes. Movements of the electrode tip cause recording instabilities while spike amplitudes decline over the weeks/months post-implantation due to glial cell activation caused by sustain...

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Veröffentlicht in:PLoS One
Hauptverfasser: Sohal, Harbaljit S., Clowry, Gavin J., Jackson, Andrew, O’Neill, Anthony, Baker, Stuart N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5082854/
https://ncbi.nlm.nih.gov/pubmed/27788240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0165606
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