Surgical extraction of human dorsal root ganglia from organ donors and preparation of primary sensory neuron cultures

Primary cultures of rodent sensory neurons are widely used to investigate the cellular and molecular mechanisms involved in pain, itch, nerve injury, and regeneration. However, translation of these preclinical findings may be greatly improved by direct validation in human tissues. We have developed...

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Bibliographic Details
Published in:Nat Protoc
Main Authors: Valtcheva, Manouela V., Copits, Bryan A., Davidson, Steve, Sheahan, Tayler D., Pullen, Melanie Y., McCall, Jordan G., Dikranian, Krikor, Gereau, Robert W.
Format: Artigo
Language:Inglês
Published: 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5082842/
https://ncbi.nlm.nih.gov/pubmed/27606776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2016.111
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