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Altered T cell phenotypes associated with clinical relapse of multiple sclerosis patients receiving fingolimod therapy
Multiple sclerosis (MS) is a T cell-mediated autoimmune disease. Fingolimod, a highly effective disease-modifying drug for MS, retains CCR7(+) central memory T cells in which autoaggressive T cells putatively exist, in secondary lymphoid organs, although relapse may still occur in some patients. Her...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5082790/ https://ncbi.nlm.nih.gov/pubmed/27752051 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep35314 |
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