Bombesin-induced gastrin release from canine G cells is stimulated by Ca2+ but not by protein kinase C, and is enhanced by disruption of rho/cytoskeletal pathways.

Isolated canine G cells in primary culture have been used to study calcium, protein kinase C (PKC), and rho/cytoskeletal-dependent intracellular pathways involved in bombesin- stimulated gastrin release. A method to obtain highly purified G cells by culture (64% G cells) after flow cytometry on elut...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Seensalu, R, Avedian, D, Barbuti, R, Song, M, Slice, L, Walsh, J H
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1997
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508278/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9276720/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119614
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