Generation and phenotype of a transgenic knockout mouse lacking the mercurial-insensitive water channel aquaporin-4.

Aquaporin-4 (AQP4) is a mercurial-insensitive, water-selective channel that is expressed in astroglia and basolateral plasma membranes of epithelia in the kidney collecting duct, airways, stomach, and colon. A targeting vector for homologous recombination was constructed using a 7-kb SacI AQP4 genom...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Main Authors: Ma, T, Yang, B, Gillespie, A, Carlson, E J, Epstein, C J, Verkman, A S
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1997
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508270/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9276712/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI231
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