Dexamethasone and supportive care with or without whole brain radiotherapy in treating patients with non-small cell lung cancer with brain metastases unsuitable for resection or stereotactic radiotherapy (QUARTZ): results from a phase 3, non-inferiority, randomised trial

BACKGROUND: Whole brain radiotherapy (WBRT) and dexamethasone are widely used to treat brain metastases from non-small cell lung cancer (NSCLC), although there have been no randomised clinical trials showing that WBRT improves either quality of life or overall survival. Even after treatment with WBR...

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Detalhes bibliográficos
Publicado no:Lancet
Main Authors: Mulvenna, Paula, Nankivell, Matthew, Barton, Rachael, Faivre-Finn, Corinne, Wilson, Paula, McColl, Elaine, Moore, Barbara, Brisbane, Iona, Ardron, David, Holt, Tanya, Morgan, Sally, Lee, Caroline, Waite, Kathryn, Bayman, Neil, Pugh, Cheryl, Sydes, Benjamin, Stephens, Richard, Parmar, Mahesh K, Langley, Ruth E
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5082599/
https://ncbi.nlm.nih.gov/pubmed/27604504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0140-6736(16)30825-X
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