A novel high mobility group box 1 neutralizing chimeric antibody attenuates drug‐induced liver injury and postinjury inflammation in mice

Acetaminophen (APAP) overdoses are of major clinical concern. Growing evidence underlines a pathogenic contribution of sterile postinjury inflammation in APAP‐induced acute liver injury (APAP‐ALI) and justifies development of anti‐inflammatory therapies with therapeutic efficacy beyond the therapeut...

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Detaylı Bibliyografya
Yayımlandı:Hepatology
Asıl Yazarlar: Lundbäck, Peter, Lea, Jonathan D., Sowinska, Agnieszka, Ottosson, Lars, Fürst, Camilla Melin, Steen, Johanna, Aulin, Cecilia, Clarke, Joanna I., Kipar, Anja, Klevenvall, Lena, Yang, Huan, Palmblad, Karin, Park, B. Kevin, Tracey, Kevin J., Blom, Anna M., Andersson, Ulf, Antoine, Daniel J., Erlandsson Harris, Helena
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2016
Konular:
Liver Injury/Regeneration
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5082559/
https://ncbi.nlm.nih.gov/pubmed/27474782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.28736
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