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Prospects for Creation of Cardioprotective and Antiarrhythmic Drugs Based on Opioid Receptor Agonists

It has now been demonstrated that the μ, δ(1), δ(2), and κ(1) opioid receptor (OR) agonists represent the most promising group of opioids for the creation of drugs enhancing cardiac tolerance to the detrimental effects of ischemia/reperfusion (I/R). Opioids are able to prevent necrosis and apoptosis...

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Detalhes bibliográficos
Publicado no:Med Res Rev
Main Authors: Maslov, Leonid N, Khaliulin, Igor, Oeltgen, Peter R., Naryzhnaya, Natalia V., Pei, Jian‐Ming, Brown, Stephen A., Lishmanov, Yury B., Downey, James M.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5082499/
https://ncbi.nlm.nih.gov/pubmed/27197922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/med.21395
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