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Muscle-specific transgenic complementation of GLUT4-deficient mice. Effects on glucose but not lipid metabolism.

We have taken the approach of introducing the muscle-specific myosin light chain (MLC)-GLUT4 transgene into the GLUT4-null background to assess the relative role of muscle and adipose tissue GLUT4 in the etiology of the GLUT4-null phenotype. The resulting MLC-GLUT4-null mice express GLUT4 predominan...

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Dettagli Bibliografici
Autori principali: Tsao, T S, Stenbit, A E, Li, J, Houseknecht, K L, Zierath, J R, Katz, E B, Charron, M J
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1997
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC508236/
https://ncbi.nlm.nih.gov/pubmed/9239415
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