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Coupling Data Mining and Laboratory Experiments to Discover Drug Interactions Causing QT Prolongation
BACKGROUND: QT-interval prolonging drug-drug interactions (QT-DDIs) may increase the risk of life-threatening arrhythmias. Despite guidelines for testing from regulatory agencies, these interactions are usually discovered after drugs are marketed and may go undiscovered for years. OBJECTIVES: Using...
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| Publicado no: | J Am Coll Cardiol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5082283/ https://ncbi.nlm.nih.gov/pubmed/27737742 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacc.2016.07.761 |
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