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Interferon-gamma deficiency prevents coronary arteriosclerosis but not myocardial rejection in transplanted mouse hearts.

We have hypothesized that T cell cytokines participate in the pathogenesis of graft arterial disease (GAD). This study tested the consequences of IFN-gamma deficiency on arterial and parenchymal pathology in murine cardiac allografts. Hearts from C-H-2(bm12)KhEg (bm12, H-2(bm12)) were transplanted i...

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Bibliographic Details
Main Authors: Nagano, H, Mitchell, R N, Taylor, M K, Hasegawa, S, Tilney, N L, Libby, P
Format: Artigo
Language:Inglês
Published: 1997
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC508221/
https://ncbi.nlm.nih.gov/pubmed/9239401
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