Human histocompatibility leukocyte antigen-binding supermotifs predict broadly cross-reactive cytotoxic T lymphocyte responses in patients with acute hepatitis.

The present study was designed to determine if highly conserved hepatitis B virus (HBV)-derived peptides that bind multiple HLA class I alleles with high affinity are recognized as cytotoxic T lymphocyte (CTL) epitopes in acutely infected patients. Peripheral blood mononuclear cells from 67 patients...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Clin Invest
Auteurs principaux: Bertoni, R, Sidney, J, Fowler, P, Chesnut, R W, Chisari, F V, Sette, A
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 1997
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508216/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9239396/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119559
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