Inhibition of constitutive nitric oxide synthase (NOS) by nitric oxide generated by inducible NOS after lipopolysaccharide administration provokes renal dysfunction in rats.

Excess NO generation plays a major role in the hypotension and systemic vasodilatation characteristic of sepsis. Yet the kidney response to sepsis is characterized by vasoconstriction resulting in renal dysfunction. We have examined the roles of inducible nitric oxide synthase (iNOS) and endothelial...

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Detaylı Bibliyografya
Asıl Yazarlar: Schwartz, D, Mendonca, M, Schwartz, I, Xia, Y, Satriano, J, Wilson, C B, Blantz, R C
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1997
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC508208/
https://ncbi.nlm.nih.gov/pubmed/9218522
Etiketler: Etiketle
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