BUB1 and SURVIVIN proteins are not degraded after a prolonged mitosis and accumulate in the nuclei of HCT116 cells

Spindle poisons activate the spindle assembly checkpoint and prevent mitotic exit until cells die or override the arrest. Several studies have focused on spindle poison-mediated cell death, but less is known about consequences in cells that survive a mitotic arrest. During mitosis, proteins such as...

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Publicat a:Cell Death Discov
Autors principals: Andonegui-Elguera, Marco A, Cáceres-Gutiérrez, Rodrigo E, Luna-Maldonado, Fernando, López-Saavedra, Alejandro, Díaz-Chávez, José, Cisneros-Soberanis, Fernanda, Prada, Diddier, Mendoza-Pérez, Julia, Herrera, Luis A
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5081682/
https://ncbi.nlm.nih.gov/pubmed/27818790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddiscovery.2016.79
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