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Accumulation of specific sterol precursors targets a MAP kinase cascade mediating cell–cell recognition and fusion
Sterols are vital components of eukaryotic cell membranes. Defects in sterol biosynthesis, which result in the accumulation of precursor molecules, are commonly associated with cellular disorders and disease. However, the effects of these sterol precursors on the metabolism, signaling, and behavior...
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Publié dans: | Proc Natl Acad Sci U S A |
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Auteurs principaux: | , , , , , , , , , |
Format: | Artigo |
Langue: | Inglês |
Publié: |
National Academy of Sciences
2016
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5081648/ https://ncbi.nlm.nih.gov/pubmed/27708165 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1610527113 |
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