Accumulation of specific sterol precursors targets a MAP kinase cascade mediating cell–cell recognition and fusion

Sterols are vital components of eukaryotic cell membranes. Defects in sterol biosynthesis, which result in the accumulation of precursor molecules, are commonly associated with cellular disorders and disease. However, the effects of these sterol precursors on the metabolism, signaling, and behavior...

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Guardat en:
Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Weichert, Martin, Lichius, Alexander, Priegnitz, Bert-Ewald, Brandt, Ulrike, Gottschalk, Johannes, Nawrath, Thorben, Groenhagen, Ulrike, Read, Nick D., Schulz, Stefan, Fleißner, André
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2016
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5081648/
https://ncbi.nlm.nih.gov/pubmed/27708165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1610527113
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