A common mutation (G-455--> A) in the beta-fibrinogen promoter is an independent predictor of plasma fibrinogen, but not of ischemic heart disease. A study of 9,127 individuals based on the Copenhagen City Heart Study.

A common mutation (G-455--> A) in the promoter region of the beta-fibrinogen gene has been associated with elevated plasma fibrinogen levels. Whether fibrinogen genotype affects plasma fibrinogen levels and risk of ischemic heart disease in the general population has not been studied. We investigate...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Tybjaerg-Hansen, A, Agerholm-Larsen, B, Humphries, S E, Abildgaard, S, Schnohr, P, Nordestgaard, B G
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508156/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9185528/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119499
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