Simultaneous delivery of Paclitaxel and Bcl-2 siRNA via pH-Sensitive liposomal nanocarrier for the synergistic treatment of melanoma

pH-sensitive drug carriers that are sensitive to the acidic (pH = ~6.5) microenvironments of tumor tissues have been primarily used as effective drug/gene/siRNA/microRNA carriers for releasing their payloads to tumor cells/tissues. Resistance to various drugs has become a big hurdle in systemic chem...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Reddy, Teegala Lakshminarayan, Garikapati, Koteswara Rao, Reddy, S. Gopal, Reddy, B. V. Subba, Yadav, J. S., Bhadra, Utpal, Bhadra, Manika Pal
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5081533/
https://ncbi.nlm.nih.gov/pubmed/27786239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep35223
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