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Serelaxin Elicits Bronchodilation and Enhances β-Adrenoceptor-Mediated Airway Relaxation

Treatment with β-adrenoceptor agonists does not fully overcome the symptoms associated with severe asthma. Serelaxin elicits potent uterine and vascular relaxation via its cognate receptor, RXFP1, and nitric oxide (NO) signaling, and is being clinically evaluated for the treatment of acute heart fai...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Lam, Maggie, Royce, Simon G., Donovan, Chantal, Jelinic, Maria, Parry, Laura J., Samuel, Chrishan S., Bourke, Jane E.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5081476/
https://ncbi.nlm.nih.gov/pubmed/27833558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2016.00406
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