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Serelaxin Elicits Bronchodilation and Enhances β-Adrenoceptor-Mediated Airway Relaxation

Treatment with β-adrenoceptor agonists does not fully overcome the symptoms associated with severe asthma. Serelaxin elicits potent uterine and vascular relaxation via its cognate receptor, RXFP1, and nitric oxide (NO) signaling, and is being clinically evaluated for the treatment of acute heart fai...

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Détails bibliographiques
Publié dans:Front Pharmacol
Auteurs principaux: Lam, Maggie, Royce, Simon G., Donovan, Chantal, Jelinic, Maria, Parry, Laura J., Samuel, Chrishan S., Bourke, Jane E.
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5081476/
https://ncbi.nlm.nih.gov/pubmed/27833558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2016.00406
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