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MicroRNA-145 Inhibits Cell Migration and Invasion and Regulates Epithelial-Mesenchymal Transition (EMT) by Targeting Connective Tissue Growth Factor (CTGF) in Esophageal Squamous Cell Carcinoma

BACKGROUND: This study investigated the mechanism of miR-145 in targeting connective tissue growth factor (CTGF), which affects the proliferation, migration, invasion, and epithelial-mesenchymal transition (EMT) of ESCC cells. MATERIAL/METHODS: A total of 50 ESCC tissues and their corresponding norm...

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Опубликовано в: :Med Sci Monit
Главные авторы: Han, Qiang, Zhang, Hua-Yong, Zhong, Bei-Long, Wang, Xiao-Jing, Zhang, Bing, Chen, Hua
Формат: Artigo
Язык:Inglês
Опубликовано: International Scientific Literature, Inc. 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5081241/
https://ncbi.nlm.nih.gov/pubmed/27771733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.897663
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