Combined Toxic Effects of Polar and Nonpolar Chemicals on Human Hepatocytes (HepG2) Cells by Quantitative Property-Activity Relationship Modeling

We determined the toxicity of mixtures of ethyl acetate (EA), isopropyl alcohol (IPA), methyl ethyl ketone (MEK), toluene (TOL) and xylene (XYL) with half-maximal effective concentration (EC(50)) values obtained using human hepatocytes cells. According to these data, quantitative property-activity r...

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Detalhes bibliográficos
Publicado no:Toxicol Res
Main Authors: Kim, Ki-Woong, Won, Yong Lim, Park, Dong Jin, Kim, Young Sun, Jin, Eun Sil, Lee, Sung Kwang
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Society of Toxicology 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5080860/
https://ncbi.nlm.nih.gov/pubmed/27818736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5487/TR.2016.32.4.337
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