Identification of naturally processed T cell epitopes from glutamic acid decarboxylase presented in the context of HLA-DR alleles by T lymphocytes of recent onset IDDM patients.

Glutamic acid decarboxylase (GAD) has been defined as a major target antigen in insulin-dependent diabetes mellitus (IDDM). To identify the molecular ligands triggering a T cell response to GAD, a panel of human GAD65-specific T lymphocyte lines was generated from peripheral blood of three recent on...

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Detalhes bibliográficos
Main Authors: Endl, J, Otto, H, Jung, G, Dreisbusch, B, Donie, F, Stahl, P, Elbracht, R, Schmitz, G, Meinl, E, Hummel, M, Ziegler, A G, Wank, R, Schendel, D J
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC508080/
https://ncbi.nlm.nih.gov/pubmed/9153283
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