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The C-terminal domain of TPX2 is made of alpha-helical tandem repeats
BACKGROUND: TPX2 (Targeting Protein for Xklp2) is essential for spindle assembly, activation of the mitotic kinase Aurora A and for triggering microtubule nucleation. Homologs of TPX2 in Chordata and plants were previously identified. Currently, proteins of the TPX2 family have little structural inf...
Enregistré dans:
| Publié dans: | BMC Struct Biol |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5080731/ https://ncbi.nlm.nih.gov/pubmed/27782824 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12900-016-0070-8 |
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