The C-terminal domain of TPX2 is made of alpha-helical tandem repeats

BACKGROUND: TPX2 (Targeting Protein for Xklp2) is essential for spindle assembly, activation of the mitotic kinase Aurora A and for triggering microtubule nucleation. Homologs of TPX2 in Chordata and plants were previously identified. Currently, proteins of the TPX2 family have little structural inf...

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Publicado en:BMC Struct Biol
Autores principales: Sanchez-Pulido, Luis, Perez, Laurent, Kuhn, Steffen, Vernos, Isabelle, Andrade-Navarro, Miguel A.
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5080731/
https://ncbi.nlm.nih.gov/pubmed/27782824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12900-016-0070-8
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