Mesenchymal stem cells with Sirt1 overexpression suppress breast tumor growth via chemokine-dependent natural killer cells recruitment

Mesenchymal stem cells (MSCs) are generally used in regenerative medicine, tissue engineering and therapy for immune disorder diseases. However, due to the immunosuppressive function of MSCs, the application of MSCs in breast cancer therapy remains limited. Sirt1 is the closest mammalian homologue o...

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Vydáno v:Sci Rep
Hlavní autoři: Yu, Yang, Liu, Yan, Zong, Chen, Yu, Qingbo, Yang, Xue, Liang, Lei, Ye, Fei, Nong, Li, Jia, Yuxian, Lu, Yongkui, Han, Zhipeng
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5080609/
https://ncbi.nlm.nih.gov/pubmed/27782173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep35998
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