Problems and Solutions in Click Chemistry Applied to Drug Probes

Small-molecule fluorescent probes have been widely used in target identification, but this method has many disadvantages. For example, the identified proteins are usually complex, and additional biochemical studies are needed to distinguish real targets from interference results. To address this pro...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Zhong, Weilong, Sun, Bo, Lu, Cheng, Yu, Hengheng, Wang, Changhua, He, Lingfei, Gu, Ju, Chen, Shuang, Liu, Yanrong, Jing, Xiangyan, Bi, Zhun, Yang, Guang, Zhou, Honggang, Sun, Tao, Yang, Cheng
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5080546/
https://ncbi.nlm.nih.gov/pubmed/27782133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep35579
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