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Biotinylation of Deoxyguanosine at the Abasic Site in Double-Stranded Oligodeoxynucleotides

Biotinylation of deoxyguanosine at an abasic site in double-stranded oligodeoxynucleotides was studied. The biotinylation of deoxyguanosine is achieved by copper-catalyzed click reaction after the conjugation of the oligodeoxynucleotide with 2-oxohex-5-ynal. The biotinylation enables visualization o...

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Bibliographische Detailangaben
Veröffentlicht in:J Anal Methods Chem
1. Verfasser: Wu, Chun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5080518/
https://ncbi.nlm.nih.gov/pubmed/27818833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/4681421
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