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Human chorionic gonadotropin hormone prevents wasting syndrome and death in HIV-1 transgenic mice.

At birth, transgenic mice, homozygous for the HIV-1 provirus pNL4-3, deleted in gag/pol, are normal in appearance and weight. Within several days after birth, the pups develop a syndrome characterized by dry, scaly, hyperkeratotic skin, growth failure, and death. The possibility that the homozygous...

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Dettagli Bibliografici
Pubblicato in:J Clin Invest
Autori principali: De, S K, Wohlenberg, C R, Marinos, N J, Doodnauth, D, Bryant, J L, Notkins, A L
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 1997
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507967/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9119991/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119310
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