Altered responses of human macrophages to lipopolysaccharide by hydroperoxy eicosatetraenoic acid, hydroxy eicosatetraenoic acid, and arachidonic acid. Inhibition of tumor necrosis factor production.

The regulation of allergic and autoimmune inflammatory reactions by polyunsaturated fatty acids and their metabolic products (eicosanoids) continues to be of major interest. Our data demonstrate that arachidonic acid 5,8,11,14-eicosatetraenoic acid (20:4n-6) and its hydroxylated derivatives 15(s)-hy...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Ferrante, J V, Huang, Z H, Nandoskar, M, Hii, C S, Robinson, B S, Rathjen, D A, Poulos, A, Morris, C P, Ferrante, A
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1997
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507960/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9077554/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119303
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