A Phase 1 Study of 4 Live, Recombinant Human Cytomegalovirus Towne/Toledo Chimera Vaccines in Cytomegalovirus–Seronegative Men

Background. Human cytomegalovirus (HCMV) infection causes disease in newborns and transplant recipients. A HCMV vaccine (Towne) protects transplant recipients. Methods. The genomes of Towne and the nonattenuated Toledo strain were recombined, yielding 4 Towne/Toledo chimera vaccines. Each of 36 HCMV...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Adler, Stuart P., Manganello, Anne-Marie, Lee, Ronzo, McVoy, Michael A., Nixon, Daniel E., Plotkin, Stanley, Mocarski, Edward, Cox, Josephine H., Fast, Patricia E., Nesterenko, Pavlo A., Murray, Susan E., Hill, Ann B., Kemble, George
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5079366/
https://ncbi.nlm.nih.gov/pubmed/27521362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiw365
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