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High content image analysis of focal adhesion-dependent mechanosensitive stem cell differentiation

Human mesenchymal stem cells (hMSCs) receive differentiation cues from a number of stimuli, including extracellular matrix (ECM) stiffness. The pathways used to sense stiffness and other physical cues are just now being understood and include proteins within focal adhesions. To rapidly advance the p...

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Detalhes bibliográficos
Publicado no:Integr Biol (Camb)
Main Authors: Holle, Andrew W., McIntyre, Alistair J., Kehe, Jared, Wijesekara, Piyumi, Young, Jennifer L., Vincent, Ludovic G., Engler, Adam J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5079280/
https://ncbi.nlm.nih.gov/pubmed/27723854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6ib00076b
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