Increased cellular expression of matrix proteins that regulate mineralization is associated with calcification of native human and porcine xenograft bioprosthetic heart valves.

Dystrophic mineralization remains the leading cause of stenotic or regurgitant failure in native human and porcine bioprosthetic heart valves. We hypothesized that cellular expression of noncollagenous matrix proteins (osteopontin, osteocalcin, and osteonectin) that regulate skeletal mineralization...

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Pubblicato in:	J Clin Invest
Autori principali:	Srivatsa, S S, Harrity, P J, Maercklein, P B, Kleppe, L, Veinot, J, Edwards, W D, Johnson, C M, Fitzpatrick, L A
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1997
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507908/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9062358/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119265
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