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Hydrogen Sulfide Regulates Krüppel‐Like Factor 5 Transcription Activity via Specificity Protein 1 S‐Sulfhydration at Cys664 to Prevent Myocardial Hypertrophy
BACKGROUND: Hydrogen sulfide (H(2)S) is a gasotransmitter that regulates multiple cardiovascular functions. Krüppel‐like factor 5 (KLF5) exerts diverse functions in the cardiovascular system. Whether and how H(2)S regulates KLF5 in myocardial hypertrophy is unknown. METHODS AND RESULTS: In our study...
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| Udgivet i: | J Am Heart Assoc |
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| Main Authors: | , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
John Wiley and Sons Inc.
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5079055/ https://ncbi.nlm.nih.gov/pubmed/27638782 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.116.004160 |
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