Efficacy and Safety of Alirocumab 150 mg Every 4 Weeks in Patients With Hypercholesterolemia Not on Statin Therapy: The ODYSSEY CHOICE II Study

BACKGROUND: The PCSK9 antibody alirocumab (75 mg every 2 weeks; Q2W) as monotherapy reduced low‐density lipoprotein‐cholesterol (LDL‐C) levels by 47%. Because the option of a monthly dosing regimen is convenient, ODYSSEY CHOICE II evaluated alirocumab 150 mg Q4W in patients with inadequately control...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Stroes, Erik, Guyton, John R., Lepor, Norman, Civeira, Fernando, Gaudet, Daniel, Watts, Gerald F., Baccara‐Dinet, Marie T., Lecorps, Guillaume, Manvelian, Garen, Farnier, Michel, Kostner, K., Lehman, S., Descamps, O., Gheyle, L., Mathieu, C., Bergeron, J., Elliott, T., Girard, G., Gupta, A., Hoag, G., Hove, J., Jeppesen, J., Kjærulf, J.H., Klarlund, K., Thomsen, K.K., Basart, D.C.G., Kooy, A., Liem, A., Swart, H., Troquay, R., Van Het Hof‐Wiersma, J, Viergever, P., Visseren, F., Doughty, R.N., Scott, R., Calvo, C., Díaz‐Díaz, J.L., Fuentes, F., Gil‐Extremera, B., Jericó, C., Matas Pericas, L., Mediavilla Garcia, J.D., Bolster, D.E., Koren, M., El Shahawy, M., Vardi, G., Weinstein, D., Zuzarte, K., Ginsberg, Henry, Robinson, Jennifer G., Rader, Daniel J., Cannon, Christopher P., Colhoun, Helen, Kastelein, John J.P., Huo, Yong, Olsson, Anders, Waters, David, Larrey, Dominique, Rosenson, Robert S., Patriarca, Peter A., Molenberghs, Geert, Tricoci, Pierluigi, Mahaffey, Kenneth W., Lopes, Renato D., Shah, Bimal R., Mehta, Rajendra H., Roe, Matthew T., Eapen, Zubin, Armaganijan, Luciana, Bertolami, Adriana, Leonardi, Sergio, Kolls, Bradley J., Jordan, J. Dedrick, Ducrocq, Grégory, Puymirat, Etienne, Mathews, Robin
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5079013/
https://ncbi.nlm.nih.gov/pubmed/27625344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.116.003421
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados