The effect of intravenous administration of a chimeric anti-IgE antibody on serum IgE levels in atopic subjects: efficacy, safety, and pharmacokinetics.

CGP 51901 is a non-anaphylactogenic mouse/human chimeric anti-human IgE antibody that binds to free IgE and surface IgE of IgE-expressing B cells but not to IgE bound to high affinity IgE receptors (Fc epsilonR1) on mast cells and basophils or low affinity IgE receptors (Fc epsilonR2) on other cells...

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Main Authors: Corne, J, Djukanovic, R, Thomas, L, Warner, J, Botta, L, Grandordy, B, Gygax, D, Heusser, C, Patalano, F, Richardson, W, Kilchherr, E, Staehelin, T, Davis, F, Gordon, W, Sun, L, Liou, R, Wang, G, Chang, T W, Holgate, S
格式: Artigo
語言:Inglês
出版: 1997
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC507895/
https://ncbi.nlm.nih.gov/pubmed/9062345
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