Alkaloids from piper longum protect dopaminergic neurons against inflammation-mediated damage induced by intranigral injection of lipopolysaccharide

BACKGROUND: Alkaloids from Piper longum (PLA), extracted from P. longum, have potent anti-inflammatory effects. The aim of this study was to investigate whether PLA could protect dopaminergic neurons against inflammation-mediated damage by inhibiting microglial activation using a lipopolysaccharide...

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Veröffentlicht in:BMC Complement Altern Med
Hauptverfasser: He, Huan, Guo, Wei-Wei, Xu, Rong-Rong, Chen, Xiao-Qing, Zhang, Nan, Wu, Xia, Wang, Xiao-Min
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2016
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5078945/
https://ncbi.nlm.nih.gov/pubmed/27776556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12906-016-1392-6
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