The adapter protein Grb10 associates preferentially with the insulin receptor as compared with the IGF-I receptor in mouse fibroblasts.

To identify receptor-associated proteins that may contribute to the specificity of insulin and IGF-I signaling responses, a mouse embryo library was screened using the yeast two-hybrid system. Multiple receptor-interactive clones encoding the SH2 domain of the adapter protein Grb10 were isolated. Su...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Laviola, L, Giorgino, F, Chow, J C, Baquero, J A, Hansen, H, Ooi, J, Zhu, J, Riedel, H, Smith, R J
Format: Artigo
Langue:Inglês
Publié: 1997
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC507889/
https://ncbi.nlm.nih.gov/pubmed/9062339
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