Misassembly of full-length Disrupted-in-Schizophrenia 1 protein is linked to altered dopamine homeostasis and behavioral deficits

Disrupted-in-schizophrenia 1 (DISC1) is a mental illness gene first identified in a Scottish pedigree. So far, DISC1-dependent phenotypes in animal models have been confined to expressing mutant DISC1. Here we investigated how pathology of full-length DISC1 protein could be a major mechanism in spor...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Mol Psychiatry
मुख्य लेखकों: Trossbach, S V, Bader, V, Hecher, L, Pum, M E, Masoud, S T, Prikulis, I, Schäble, S, de Souza Silva, M A, Su, P, Boulat, B, Chwiesko, C, Poschmann, G, Stühler, K, Lohr, K M, Stout, K A, Oskamp, A, Godsave, S F, Müller-Schiffmann, A, Bilzer, T, Steiner, H, Peters, P J, Bauer, A, Sauvage, M, Ramsey, A J, Miller, G W, Liu, F, Seeman, P, Brandon, N J, Huston, J P, Korth, C
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Nature Publishing Group 2016
विषय:
Original Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5078859/
https://ncbi.nlm.nih.gov/pubmed/26754951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2015.194
टैग : टैग जोड़ें
कोई टैग नहीं, इस रिकॉर्ड को टैग करने वाले पहले व्यक्ति बनें!

समान संसाधन