Peroxisome Proliferator-Activated Receptor α Reduces Endothelin-1-Caused Cardiomyocyte Hypertrophy by Inhibiting Nuclear Factor-κB and Adiponectin

Peroxisome proliferator-activated receptor α (PPARα) plays a role in the pathogenesis of cardiac hypertrophy, although its underlying mechanism remains unclear. The purpose of this study was to evaluate the effect of PPARα activation on endothelin-1- (ET-1-) caused cardiomyocyte hypertrophy and expl...

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Udgivet i:Mediators Inflamm
Main Authors: Jen, Hsu-Lung, Liu, Po-Len, Chen, Yung-Hsiang, Yin, Wei-Hsian, Chen, Jaw-Wen, Lin, Shing-Jong
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5078655/
https://ncbi.nlm.nih.gov/pubmed/27807394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/5609121
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