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Cisplatin selects for stem-like cells in osteosarcoma by activating Notch signaling

Notch signaling regulates normal stem cells and is also thought to regulate cancer stem cells (CSCs). Recent data indicate that Notch signaling plays a role in the development and progression of osteosarcoma, however the regulation of Notch in chemo-resistant stem-like cells has not yet been fully e...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Yu, Ling, Fan, Zhengfu, Fang, Shuo, Yang, Jian, Gao, Tian, Simões, Bruno M., Eyre, Rachel, Guo, Weichun, Clarke, Robert B.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5078075/
https://ncbi.nlm.nih.gov/pubmed/27102300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8849
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