UBAP2 negatively regulates the invasion of hepatocellular carcinoma cell by ubiquitinating and degradating Annexin A2

The ubiquitin-dependent proteasomal degradation of proteins controls signaling and cellular survival. In this study, we found that ubiquitin associated protein 2 (UBAP2) was significantly downregulated in hepatocellular carcinoma (HCC) tissues compared with adjacent normal tissues. Furthermore, high...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Bai, Dou-Sheng, Wu, Chao, Yang, Liu-Xiao, Zhang, Chi, Zhang, Peng-Fei, He, Yi-Zhou, Cai, Jia-Bin, Song, Zheng-Ji, Dong, Zhao-Ru, Huang, Xiao-Yong, Ke, Ai-Wu, Shi, Guo-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5078065/
https://ncbi.nlm.nih.gov/pubmed/27121050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8783
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