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Palmitoylation regulates the intracellular trafficking and stability of c-Met
c-Met is a receptor tyrosine kinase whose activity can promote both mitogenic and motogenic phenotypes involved in tissue development and cancer progression. Herein, we report the first evidence that c-Met is palmitoylated and that palmitoylation facilitates its trafficking and stability. Inhibition...
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| Veröffentlicht in: | Oncotarget |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Impact Journals LLC
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5078042/ https://ncbi.nlm.nih.gov/pubmed/27081699 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8706 |
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