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Local ventromedial hypothalamus glucose perfusion blocks counterregulation during systemic hypoglycemia in awake rats.

The ventromedial hypothalamic nucleus (VMH) is necessary for the integrated hormonal response to hypoglycemia. To determine the role of the VMH as a glucose sensor, we performed experiments designed to specifically prevent glucopenia in the VMH, while producing hypoglycemia elsewhere. We used awake...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Principais autores: Borg, M A, Sherwin, R S, Borg, W P, Tamborlane, W V, Shulman, G I
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 1997
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507804/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9006005/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119165
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