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Interferon-gamma differentially regulates interleukin-12 and interleukin-10 production in leprosy.

The ability of monocytes to influence the nature of the T cell response to microbial pathogens is mediated in part by the release of cytokines. Of particular importance is the release of IL-12 and IL-10 by cells of the monocyte/macrophage lineage upon encountering the infectious agent. IL-12 promote...

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Détails bibliographiques
Publié dans:J Clin Invest
Auteurs principaux: Libraty, D H, Airan, L E, Uyemura, K, Jullien, D, Spellberg, B, Rea, T H, Modlin, R L
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 1997
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507801/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9006002/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119162
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