Osteopontin is a multi-faceted pro-tumorigenic driver for central nervous system lymphoma

Osteopontin (OPN) is the most upregulated gene in primary central nervous system lymphoma (PCNSL) compared to non-CNS diffuse large B cell lymphoma (DLBCL). We show here that OPN is a key mediator of intracerebral tumor growth, invasion, and dissemination in CNS lymphoma, and that these effects depe...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Yushi, Qiu, Li, Zhimin, Von Roemeling, Christina A., Doeppler, Heike, Marlow, Laura A., Kim, Betty Y.S., Radisky, Derek C., Storz, Peter, Copland, John A., Tun, Han W.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5078004/
https://ncbi.nlm.nih.gov/pubmed/27050077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8537
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