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Applications of CRISPR Genome Engineering in Cell Biology

Recent advances in genome engineering are starting a revolution in biological research and translational applications. The CRISPR-associated RNA-guided endonuclease Cas9 and its variants enable diverse manipulations of genome function. In this review, we describe the development of Cas9 tools for a...

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Publicado en:Trends Cell Biol
Main Authors: Wang, Fangyuan, Qi, Lei S.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5077632/
https://ncbi.nlm.nih.gov/pubmed/27599850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2016.08.004
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